INVESTIGATING THE MULTISCALE IMPACT OF ENVIRONMENTAL FACTORS ON THE INTEGRATED USE OF DOCKLESS BIKE-SHARING AND URBAN RAIL TRANSIT

Investigating the Multiscale Impact of Environmental Factors on the Integrated Use of Dockless Bike-Sharing and Urban Rail Transit

Dockless bike-sharing (DBS) is an effective solution to the “first and last mile” problem in urban transportation.It can be integrated with urban rail transit (URT) to provide passengers with more convenient travel services.This study focuses on the integrated use of DBS and URT in Shenzhen, utilising a multi-buffer zone approach to identify DB

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Inducible expression of interleukin-12 augments the efficacy of affinity-tuned chimeric antigen receptors in murine solid tumor models

Abstract The limited number of targetable tumor-specific antigens and the immunosuppressive nature of the microenvironment within solid malignancies represent major barriers to the success of chimeric antigen receptor (CAR)-T cell therapies.Here, using epithelial cell adhesion molecule (EpCAM) as MICELLAR WATER a model antigen, we used alanine scan

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Peptide IC-20, encoded by skin kininogen-1 of the European yellow-bellied toad, Bombina variegata, antagonizes bradykinin-induced arterial smooth muscle relaxation

Objectives: The objectives were to determine if the Fridge Door Handle Plug skin secretion of the European yellow-bellied toad (Bombina variegata), in common with other related species, contains a bradykinin inhibitor peptide and to isolate and structurally characterize this peptide.Materials and Methods: Lyophilized skin secretion obtained from th

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